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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f973bf7a49a779be6f41ff45f65a571720fd7cfee50858f39a7f3252a07aa70d' 
  AND token = 'eb7etUS5mH+PACT1XEX8vLOcMQbHNVs/AN429Hl9Kyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}