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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07ec580c03635ad35cba642dabf5c8a7bf7f62de9c6420a08b71d77a2dfe0c06' 
  AND token = 'PNGKS6zWc+IXNnIU7xQgTA6b0GKMl0W2C1UgbbPc2Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}