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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a0744ff0c5f944a8219cd0b3ee8c7e02c79aa59fb89fd58bbf388a23e46391' 
  AND token = 'nM7WQuPTKHOlHRUymSPqh8DocWIOdhAL1WR7MhgE/So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}