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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b8d3dbfb21d5bc07c3bf155abeda1f950d71297ad20ea5d04ad3718b4acc51' 
  AND token = '0kJyVq73/JxSDMZo2UtGJz9v4l1iBSa0jOvK9ti/Dp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}