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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e161bbd9b73c7b3b28455c2dff6a7826431ff6aeaf8fd1a3185b9badad8d8cbe' 
  AND token = 'cM4ZGtiLHbyfdagoHxW1B5jIzw4lmwpVfj3KlAOc9UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}