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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8439924db5ecf427d6def3c8f9eb98f41fe045731895a43d268b4cce1e1ee724' 
  AND token = 'V+Wnyv9cPDuj1/l7r7DZIdvgyOPQkdf9DuJya5H4iPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}