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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257c3c106d557ebd48f9d6c02d1519274d858b7964be2bb8871a3777828907af' 
  AND token = 'zS0L0+Oionbj8v002GfyH1m9wdDt6ZB+JBEd3SQZQxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}