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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a220ec2307266845ac7581ab49430068b42cdfce7c1b1732f4b063b647be6903' 
  AND token = 'EwKyKEHvyY881hs/I1ii7XVckhoAHm5oGTWk256C3LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}