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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824ec3ccf1482680864906042c89eefd12d9f6e873a64f3e64400418c7d25c68' 
  AND token = '9w9GjdnEdWA7F0LIWUP2X/clOGsSfgJwH6zgwUPNUv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}