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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64eebb304510e06b835f3921df08f17398542d9c0ad689ac56382cb56f411eff' 
  AND token = 'mOkvKjIKjJc0lJm5nNFtMKYLjLHZyuv7boRCQreZjfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}