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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5739ccee66673b0811f6999dba6e929fb8604ac145b47298867f5922b68e5fc1' 
  AND token = '89Lse6mBfc6SConTCyxWEJd0bP4IkchXY035A7MGtKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}