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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a767c5384143915ef6da9d35c0222bb3a9d04e45a32a94da5850af233580df' 
  AND token = 'e8Zr4jPWYN0WISxzsLca4UH3qL/SHILKC/IVyNuK+4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}