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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aaa4e34d51f0193af44dc335762d5c0de90a8fbd89eb934e014a4cb11a43849' 
  AND token = 'yo37viuUjQHEQBd6NI2NEsSankoLXbC8qbbFkwC3N9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}