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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4286fc22fd8fdb2a263e842d43b70de3c0bb4e2ebff8978170f6c29421688fd' 
  AND token = 'sbYHQPcrHmdmaSsyfOB/jEHMtmhF3/M3T1dKip9xSHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}