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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caeab7fca8b0b8733dd6cfcbcd96c6ab1882051a7a1cc415820347bf3ea82189' 
  AND token = 'UYVDgqpsneg+KNzYNxgF0h3Kua1bYLt2YT1Ij3cU/kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}