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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2947cbf5fd256637580ab9682e2194de83ea0ccea44e5723b4d282274b573a6' 
  AND token = 'nNEBkT0LxOLpISoWN+K8uKErSHc9Wc3o/lxTBuV5AME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}