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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f60544f594654fe79c2f6df294129405860b9b4983327634b3db5915ba1a77' 
  AND token = 'CnFgzNmIZqOv5P0AcZ8abOktU8aC8Z6aEmTdKS+fk7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}