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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e32048e053b58ebf5c43581f4ce0f2e6c1e241236faf48d710b3ce0feb021d' 
  AND token = 'LZ5G7NcAsXxEely3tCiBszxLJy1h/Vc3GCacQDyFcNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}