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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df52643fe3199db6a0fdc6d30378a084d694af17ce06fa8deb9fdeaf8ea89f2' 
  AND token = 'dNVI+qLiCf4ULAH8+2gF4l8Vag4A6hMDLkvZSNnN2wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}