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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55b4f00a3896c0a59e493eb329621c2549d816671fb0fa2750fe45be48bc4d1b' 
  AND token = 'FzY7P6pXbokqvETgYFuIY09nt6fFC48oFOeXq3VDWlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}