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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165bfb886f73dcf5a73b7d9123a35d5b392f977a7ec4a051e03e91fe34df335d' 
  AND token = 'npnGEH86bQ1T38MFmlJtG7f4V60s5QFDfh8xA1GqvyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}