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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c56417f64a68482201ca4391bc4abeeea0e17d07024fcd4e2adabe3f29097b' 
  AND token = 'mG5A7tngtO9CW+thgPD0fES84Z0NsbUCURvvjJF0mk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}