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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6376b6389b9a2200bdd88d4378b8a590c29329899f569d253d003fd1a933d99a' 
  AND token = 'nzfBD8geIqea5rb6PmbOJJlDHiQYAwa1+in1Z/WPJ+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}