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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74506948e12e5c2f52306f0f52b9bf639f4e1e7ff46912bb59f4fe57e68503c9' 
  AND token = 'CJVAyDLdNC/eu5L/zsyBLVZyJ0iVBrje5eBVVJU9FLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}