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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328c13b69ee12f9fed925c22b1a0febee41e8ef5964e7db2339aa6444731997b' 
  AND token = '80hPvVuDahKn8Ax/m6yS9Ew2kSPEKUDH+n5Riqkii0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}