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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '732311730f4f1ad13cca58fbe9b579614d54521939ea5b1fa169d91186a496bb' 
  AND token = '0ez9KTmHQ1SbAdzkURwLV1hdoAYLWcw9N+wltsiEOPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}