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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f840f8855005d5c7bf3203c161c74435a25aa8eb95ea24933448b39c66ef8f' 
  AND token = 'LBfy6tcJg1L/zcoHa1QLP8Kz8RRadrmy3qLhcBp/8A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}