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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7654ca01e8821c822951002bdf3607c7abc38a09cf47b4a415e0fde0bc92be46' 
  AND token = 'fvk38+gHSlN1EbfEIW2WdwLn6y/CWeMMz7Ugvo1q2pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}