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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6857e4d230a724b621667a5f5ffeeb71d787fb18c2b931dab51f0d240c5b682a' 
  AND token = 'eJEfs2uLt1TdMOS2xiF329ZHqsrDHH0KJSWY9uut5/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}