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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780c4ea4a3dc03a2a39567243dc20867903beb5b4737c4ca738f997184a73be7' 
  AND token = 'JNzZNsC7WAHp5epIU5odJXceIYCQ1v3hFf8/9lM/FjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}