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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0da46d4536300f5190953d5ea864e2cc4f0d86c56a99f86ff263277c5016b3f2' 
  AND token = 'ptarv8rMdMdliPp+Mg2tPJSAKvHAqgS6bLbg/9Mi2Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}