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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf251f13d4ef6f9b1a024d9746eacc8990bcc202bf45486f6db278b00a43e42' 
  AND token = '+FaT7k19EB8Tw3zClTXCGwpKVwtF02vGJ2ZygDfdCLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}