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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc3b640a674252e6e75203ee7d5634a8ae8ee791bb71a1c214f024c2c8e8d33' 
  AND token = 'ptZfV6qcSPDQRA0j011HP+lsgj23QnQT3gYKhJGcqiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}