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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75b2622622ad6d08b5eb8a24a5da64ac84de24e5bfd3fc28b1c8456eb102c42' 
  AND token = 'iDQYuROQOsApGipOqh3GCR4cIVAzxo8iUL/32gGbqZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}