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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6edc57eb73a5eac6388f7c05f8b34138f46e0252882c27c9dd3c62fd2f781ef' 
  AND token = 'tTRknSB3OVWvrmdwdVC+Y2SlQPlTXOnj4AdsFPiN1ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}