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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7e3d37eaf813fff8d0273594a0110267b59ebf9c06bcb4592321dadc1e606cc' 
  AND token = 'ltmYGfik5B3LyRd5j+FoLZ2ehKgo1c5Bq0gf99HYTmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}