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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb5282faf512fd94de3d7eeaf99731e6c5db32e5b94d30608079a65e7a5a8634' 
  AND token = 'dQAGokD5+HWS88PftHe0jFcE9zyyROfQ3pchTOUqIQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}