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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f283ccf3ff46a9a48449c427131752921a595eb20f00f78cbfdbe2a9b5e097' 
  AND token = 'kc3ZYWbYHkvGJNtsnDkLT9M+vtMtYRSC7He5waAPmPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}