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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686a3da15f90e52e8c9462656642808314ebc8cf0e41303a3840017c4daba04e' 
  AND token = 'BBpxtNkpG3bWN/F0kHA/LCXGcntSdUjQ1KaFjFhlf7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}