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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc812410f8a39989267472be974d928dfd9618977de5adf5c8b4a2171b91163' 
  AND token = 'K6ryWh52VZMEWxON7SxxjS+3MGvn/cNAxQDV+Hcha1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}