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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57293af22d7c73703ead847dd268720fe1406e607a9bf4e7f80e9e73dd1d8eb5' 
  AND token = 'Q3mOuM8Pjb99IyjRvaEJHBX7GK7ba2bMAyia/D+QDy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}