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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eee96cd3be0c9f5af54313aae89a7c4d639b4e2794c6f229ca1fc6631142812' 
  AND token = 'o+hck7BW/TDnzCeq+Tz5kzGjuOc3jMrz3QAXNCy1IQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}