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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4806e25ca0ebf8e05ca56a40eba4d374983ed7d43ad84941991e0b83b847bdbe' 
  AND token = 'AlxT4sTCZhUQ15+Grjz/GsV8AdwyJ7O2fJo34p1URAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}