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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3da03292deb08db15c12e1af4bb87a5652aa8273638056dc753ed2fe3c274e' 
  AND token = 'AXLFfvVjqFiN1Q0t+gndE2V4KmfsPiX2l6VLdGvZ96g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}