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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c165bc43c142fbe80c925303e7f88f68d5c3c581f28972c23d7546c44dcf7e' 
  AND token = 'gGDpOgdi0vId7xjeFA0OCyedx1eALWWs3Pw3Gx9NKjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}