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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de24aa18190054efe31b94b6d4499dc9beb8ecd9efb4ab47db4031e11c205583' 
  AND token = 'vDpnVhyjKR3unoyYLP3RUeZuaMQ0hGMfJNeHG2sMZMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}