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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b603067e4c8bad41c5e5fd2922628fdf42ac2164b3e473cda7ee7b37581b0223' 
  AND token = 'MxHnOaC6Hd/Fox/rpkq09C3XRbqtJafscvhTuSDU8lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}