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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '867bef52a527e12d368fb87b55e384032b1ebe0a0f1883c3bbb3a80820381879' 
  AND token = 'jKNiYmwzVTB8JR+UJiBLCwi21Fy5xzdMrkjxMUkwW5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}