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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57192381107afd5ce3da0fac42a11b9f6a436d4b138a77bc82ec395b8b389e7' 
  AND token = 'O5PSQfd+1nvjDY7tBXCIQ+H1YTjqTG/uvTH7YtjcrSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}