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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de79875f388a401e1100f83570957467783dbf5847a843de2ef8b040637ec4c9' 
  AND token = 'DEyAjRogfze2WRrfM1+YvEtviWosXvAIh5UCNlM6dAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}